Androgen Receptor Upregulation Mediates Radioresistance after Ionizing Radiation
نویسندگان
چکیده
منابع مشابه
Androgen Receptor Upregulation Mediates Radioresistance after Ionizing Radiation.
Clinical trials have established the benefit of androgen deprivation therapy (ADT) combined with radiotherapy in prostate cancer. ADT sensitizes prostate cancer to radiotherapy-induced death at least in part through inhibition of DNA repair machinery, but for unknown reasons, adjuvant ADT provides further survival benefits. Here, we show that androgen receptor (AR) expression and activity are d...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2015
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-15-0892